Transformation of commensal to a pathogen: Blood stream infection due to coagulase negative staphylococci among patients attending tertiary care hospital in North India

Aim of this study was to know the prevalence Coagulase Negative Staphylococci (CoNS) in Blood Stream Infection (BSI) among patients attending a Superspeciality hospital North India. Objective compare incidence CoNS ICU and ward suffering from BSI their antimicrobial susceptibility pattern. This retrospective based conducted Microbiology Department, Dr. Ram Manohar Lohia Institute Medical Sciences, Lucknow for period two years (January, 2017 -December, 2018). samples total 6498 Out-Patient, In-Patient Intensive care unit departments were subjected aerobic anaerobic bacterial culture. Culture positive broth subcultured on Agar MacConkey isolate pathogens pure Pure cultured isolates tested pattern by Kirby Bauer Disk Diffusion method as per CLSI 2018. During period, out 3284 3214 2018, 663 595 found be culture respectively.Staphylococci isolated 636 (9.78%) (10.2% 9.2% Staphylococcus aureus 18.8% 81.2% Staphylococcal isolates. Among 70.7% Methicillin Resistant (MRCoNS). observed major cause compared aureusThe significance CONS bacteremia should evaluated better light clinical profile patient. Better screening infection control practices future can decrease rate methicillin resistant our centre.